Invitrogen™ mGluR4 Monoclonal Antibody (OTI6D1)

Catalog No.	Quantity
PIMA527293	100 μL

Catalog No. PIMA527293 Supplier Invitrogen™ Supplier No. MA527293

Description

Mouse Monoclonal Antibody

mGluR4 Monoclonal Antibody for Western Blot, IHC (P)

The Metabotropic Glutamate Receptor mGluR4/GRM4 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties.

Specifications

• Antigen: mGluR4
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI6D1
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: GRM4
• Gene Accession No.: Q14833
• Gene Alias: G protein-coupled receptor GRM4; G protein-coupled receptor, family C, group 1, member D; glutamate metabotropic receptor 4; glutamate receptor; glutamate receptor, metabotropic 4; GPRC1D; GRM4; Metabotropic glutamate receptor 4; mGlu4; MGLUR4
• Gene Symbols: GRM4
• Host Species: Mouse
• Immunogen: Human recombinant protein fragment corresponding to amino acids 126-407 of GRM4 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2914
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a