Invitrogen™ MGST2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106675

Catalog No. PIPA5106675

Description

Antibody detects endogenous levels of total MGST2.

MGST2 (Microsomal glutathione S-transferase 2) is a 147 amino acid protein encoded by the human gene MGST2. MGST2 can catalyze the production of LTC4 (leukotriene C4) from LTA4 (leukotriene A4) and reduced glutathione. It can also catalyze the conjugation of 1-chloro-2,4-dinitrobenzene with reduced glutathione. MSGT2 is a multi-pass membrane protein found as a homodimer. MGST2 belongs to the MAPEG family and is expressed in liver, spleen, skeletal muscle, heart, adrenals, pancreas, prostate, testis, fetal liver, and fetal spleen. It has very low expression in lung, brain, placenta and bone marrow. Also, MGST2 is the only GST expressed in human umbilical vein endothelial cells (HUVECs).

Specifications

• Antigen: MGST2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MGST2
• Gene Alias: FLJ27438; glutathione peroxidase MGST2; GST2; leukotriene C4 synthase MGST2; MGC14097; MGST2; MGST-II; Microsomal glutathione S-transferase 2; microsomal glutathione S-transferase II; microsomal GST-2; Microsomal GST-II; Unknown (protein for MGC:127901)
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 211666, 295037, 4258
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q99735
• Gene Symbols: MGST2
• Immunogen: A synthesized peptide derived from human MGST2(Accession Q99735), corresponding to amino acid residues Y21-G71.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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