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Invitrogen™ MIB1 Polyclonal Antibody
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Catalog No. PIPA572810
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100 μg
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Catalog No. Quantity
PIPA572810 100 μg
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Catalog No. PIPA572810 Supplier Invitrogen™ Supplier No. PA572810
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Description

Rabbit Polyclonal Antibody

MIB1 Polyclonal Antibody for Western Blot, ICC/IF, ELISA

MIB is an E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. This protein positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. MIB probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MIB1
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene MIB1
Gene Accession No. Q80SY4, Q86YT6
Gene Alias DAPK-interacting protein 1; DAPK-interacting protein-1; DIP1; DIP-1; E3 ubiquitin-protein ligase MIB1; E430019M12Rik; KIAA1323; LVNC7; MIB; MIB1; Mind bomb homolog 1; mind bomb-1; mindbomb E3 ubiquitin protein ligase 1; mindbomb homolog 1; mindbomb homolog 1 (Drosophila); mKIAA1323; RING-type E3 ubiquitin transferase MIB1; skeletrophin; ubiquitin ligase mind bomb; zinc finger ZZ type with ankyrin repeat domain protein 2; ZZANK2; ZZZ6
Gene Symbols MIB1
Host Species Rabbit
Immunogen MIB1 antibody for a 19 amino acid peptide near the carboxy terminus of human MIB1. The immunogen is within amino acids 920 - 970 of MIB1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 225164, 307594, 57534
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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