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  8. Miconazole, 97%

Miconazole, 97%

Catalog No. AAJ6087203
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Catalog No. AAJ6087203 Supplier Thermo Scientific Chemicals Supplier No. J6087203
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Description

Inhibits cytochrome P450-dependent 14-alpha-demethylase | CAS: 22916-47-8 | C18H14Cl4N2O | 416.12 g/mol

Miconazole, is used as an antifungal inhibitor of aromatase. Miconazole has been shown to promote remyelination of neurons in chronic progressive multiple sclerosis mouse models. Miconazole is mainly used externally for the treatment of athlete's foot, ringworm, and jock itch. Internal application is used for oral or vaginal thrush (yeast infection). The oral gel may also be used for the lip disorder angular cheilitis. It is also used in photography.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Freely soluble in alcohols or acetone. Also soluble in DMF or chloroform. Insoluble in water

Notes
Protect from light. Store in well-closed containers.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 22916-47-8
Molecular Formula C18H14Cl4N2O
Molecular Weight (g/mol) 416.12
MDL Number MFCD00216019
InChI Key BYBLEWFAAKGYCD-UHFFFAOYNA-N
Synonym miconazole, monistat, monistat iv, daktarin iv, miconazolo, miconazolum, miconazol, minostate, dactarin, monistat-derm
PubChem CID 4189
ChEBI CHEBI:82892
IUPAC Name 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
SMILES ClC1=CC=C(COC(CN2C=CN=C2)C2=CC=C(Cl)C=C2Cl)C(Cl)=C1

Specifications

Melting Point 83°C to 97°C
Color White
Quantity 1 g
Sensitivity Light sensitive
Merck Index 14,6178
Solubility Information Freely soluble in alcohols or acetone; Also soluble in DMF or chloroform; Insoluble in water
Formula Weight 416.13
Percent Purity 99%
Physical Form Powder
Chemical Name or Material Miconazole

Safety and Handling

Hazard Category H302-H334
Hazard Statement GHS H Statement
H302-H317
Harmful if swallowed.
May cause an allergic skin reaction.
Precautionary Statement P261-P264b-P270-P285-P301+P312-P304+P341-P330-P342+P311-P501c
EINECSNumber 245-324-5
RTECSNumber NI4770000
TSCA No
Recommended Storage Store at -20°C
SDS

RUO – Research Use Only

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