Miconazole, 97%

Description

Inhibits cytochrome P450-dependent 14-alpha-demethylase | CAS: 22916-47-8 | C18H14Cl4N2O | 416.12 g/mol

Miconazole, is used as an antifungal inhibitor of aromatase. Miconazole has been shown to promote remyelination of neurons in chronic progressive multiple sclerosis mouse models. Miconazole is mainly used externally for the treatment of athlete's foot, ringworm, and jock itch. Internal application is used for oral or vaginal thrush (yeast infection). The oral gel may also be used for the lip disorder angular cheilitis. It is also used in photography.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Freely soluble in alcohols or acetone. Also soluble in DMF or chloroform. Insoluble in water

Notes
Protect from light. Store in well-closed containers.

Specifications

Chemical Identifiers

• CAS: 22916-47-8
• Molecular Formula: C18H14Cl4N2O
• Molecular Weight (g/mol): 416.12
• MDL Number: MFCD00216019
• InChI Key: BYBLEWFAAKGYCD-UHFFFAOYNA-N
• Synonym: miconazole, monistat, monistat iv, daktarin iv, miconazolo, miconazolum, miconazol, minostate, dactarin, monistat-derm
• PubChem CID: 4189
• ChEBI: CHEBI:82892
• IUPAC Name: 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
• SMILES: ClC1=CC=C(COC(CN2C=CN=C2)C2=CC=C(Cl)C=C2Cl)C(Cl)=C1

• Melting Point: 83°C to 97°C
• Color: White
• Quantity: 1 g
• Sensitivity: Light sensitive
• Merck Index: 14,6178
• Solubility Information: Freely soluble in alcohols or acetone; Also soluble in DMF or chloroform; Insoluble in water
• Formula Weight: 416.13
• Percent Purity: 99%
• Physical Form: Powder
• Chemical Name or Material: Miconazole

Safety and Handling

Hazard Category	H302-H334
Hazard Statement	GHS H Statement H302-H317 Harmful if swallowed. May cause an allergic skin reaction.
Precautionary Statement	P261-P264b-P270-P285-P301+P312-P304+P341-P330-P342+P311-P501c
EINECSNumber	245-324-5
RTECSNumber	NI4770000
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only