Thermo Scientific™ Micrococcal Nuclease (300 U/μL)

Description

Digest single-stranded and double-stranded DNA and RNA with Thermo Scientific™ Micrococcal Nuclease (S7 Nuclease), an endo-exonuclease.

Micrococcal Nuclease (S7 Nuclease) is a relatively nonspecific endo-exonuclease that digests single-stranded and double-stranded nucleic acids, but is more active on single-stranded substrates. Cleavage of DNA or RNA occurs preferentially at AT or AU-rich regions, yielding mononucleotides and oligonucleotides with terminal 3'-phosphates. The enzyme's activity is strictly dependent on Ca²⁺.

Applications

• Hydrolysis of nucleic acids in crude cell-free extracts
• Sequencing of RNA
• Studies of chromatin structure
• A model for protein folding and for structure-function studies

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Specifications

• Concentration: 300 U/μL
• Enzyme: Nuclease
• Quantity: 8,000 units
• Product Type: Micrococcal Nuclease

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only. Not for use in diagnostic procedures.