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Invitrogen™ MIF Polyclonal Antibody
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Catalog No. PIPA527343
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100 μL
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PIPA527343 100 μL
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Catalog No. PIPA527343 Supplier Invitrogen™ Supplier No. PA527343
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Molt-4, mouse brain. Predicted reactivity: Mouse (89%), Rat (90%), Pig (94%), Sheep (91%), Rhesus Monkey (100%), Bovine (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MIF (macrophage migration inhibitory factor) was one of the first cytokine activities to be discovered and was initially described as a T cell-derived factor that inhibits the random migration of macrophages (Weiser 1989). Recently, MIF was rediscovered as a pituitary hormone that act as the counterregulatory hormone for glucocorticoid action within the immune system (Bernhagen 1993, Mitchell 1995). MIF was released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secreted MIF counter-regulates the immunosuppressive effects of steroids on immune cell activation and cytokine production (Bucala 1998). MIF plays a critical role in the host control of inflammation and immunity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MIF
Applications ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Mif
Gene Accession No. P14174, P30904, P34884
Gene Alias cytokine; delayed early response protein 6; DER6; GIF; GLIF; glutathione-binding 13 kDa protein; Glycosylation-inhibiting factor; HGNC:7097; L-dopachrome isomerase; L-dopachrome tautomerase; macrophage migration inhibitory factor; macrophage migration inhibitory factor (glycosylation-inhibiting factor); MGC107654; Mif; MMIF; phenylpyruvate tautomerase
Gene Symbols Mif
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human MIF. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17319, 4282, 81683
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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