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Cayman Chemical MIFhumnrecombInt 100ug

Supplier: Cayman Chemical 14493100 UG

An inhibitor of SUR1/Kir6.2 SUR2A/Kir6.2 and SUR2B/Kir6.2 (IC50s 3 5.4 and 7.3 nM respectively in Xenopus oocytes expressing the mouse receptor) induces InsR complex dissociation and insulin degradation in HepG2 cells at 20 UM decreases blood glucose and plasma insulin levels in a KKAy mouse model of insulin-resistant type 2 diabetes at 0.05 mg/kg per day reduces HbA1c levels in the same model at 0.5 mg/kg per day
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