Invitrogen™ Mimecan Monoclonal Antibody (2G4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524417

Catalog No. PIMA524417

Description

Peptide Sequence: KSRGIKANAF KKLNNLTFLY LDHNALESVP LNLPESLRVI HLQFNNIASI TDDTFCKAND TSYIRDRIEE IRLEGNPIVL GKHPNSFICL KRLPIGSYF.

Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta. Mimecan is a small proteoglycan which contains tandem leucine-rich repeats. Mimecan is encoded by the OGN gene, a member of the small leucine-rich proteoglycan (SLRP) family of proteins. Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta (TGF-beta-1 or TGF-beta-2) and may regulate osteoblast differentiation. High expression of mimecan protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants of mimecan. Alternatively spliced transcript variants that encode mimecan have been found.

Specifications

• Antigen: Mimecan
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: OGN
• Gene Alias: 3110079A16Rik; corneal keratan sulfate proteoglycan; mimecan; mimecan proteoglycan; mimican; OG; Ogn; OIF; Osteoglycin; osteoglycin/mimecan; osteoinductive factor; SLRR3A
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4969
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA
• Clone: 2G4
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P20774
• Gene Symbols: OGN
• Immunogen: OGN (NP_148935.1, 200 a.a. ~ 298 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ