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Invitrogen™ Mist1 Monoclonal Antibody (6E8/A12/C11P1)
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Catalog No. MA1517
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100 μg
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MA1517 100 μg
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Catalog No. MA1517 Supplier Invitrogen™ Supplier No. MA1517
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Description

Mouse Monoclonal Antibody

MA1-517 detects Mist1 from mouse and human samples. MA1-517 has been successfully used in Western blot, immunohistochemistry procedures. The antibody reactivity in IP and ChIP is weaker than in other applications. By Western blot, MA1-517 detects a ~29 kDa band representing Mist1. The MA1-517 immunogen is mouse Mist1, C-terminus residues 175-197.

Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Mist1
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 6E8/A12/C11P1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Bhlha15
Gene Accession No. Q7RTS1, Q9QYC3
Gene Alias 1810009C13Rik; basic helix-loop-helix domain containing, class B, 8; basic helix-loop-helix family member a15; basic helix-loop-helix family, member a15; Basic helix-loop-helix transcription factor (bHlH); bHlH; BHLHA15; BHLHB8; Class A basic helix-loop-helix protein 15; class B basic helix-loop-helix protein 8; class II bHLH protein MIST1; MIST1; MIST-1; Muscle, intestine and stomach expression 1
Gene Symbols Bhlha15
Host Species Mouse
Immunogen Mouse Mist1, C-terminus residues 175-197.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 168620, 17341
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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