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Novus Biologicals™ Mitomycin C Inhibitor
SDP

Catalog No. NB3258 Shop All R&D Systems Products
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Quantity:
10 mg
Catalog No. Quantity
NB3258 10 mg
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Catalog No. NB3258

Supplier: Novus Biologicals™ NB3258

Description

Low molecular weight, organic compound that may help regulate biological process.

Biological Activity:R-(-)-enantiomer of gossypol. Mimics the BH3 domains of Bcl-2, Bcl-XL and Mcl-1. Disrupts heterodimerization of Bcl-2 with proapoptotic family members. Induces apoptosis in vitro through activation of caspase-9; cytotoxic to multiple myeloma and drug-resistant cell lines. Delays onset of androgen-independent growth of VCaP prostate cancer xenografts in vivo.

Storage: Store at 4°C.

Note: Inhibitors are guranteed for 1 year from date of receipt.

Specifications

Description CAS: 50-07-7
Formulation C15H18N4O5
For Use With (Application) Inhibits apoptosis
Quantity 10 mg
Product Type Inhibitors
Molecular Weight (g/mol) 334.33g/mol
Solubility Soluble to 5mM in water, 100mM in DMSO
Content And Storage 4°C
Target Mitomycin C
Color Dark Purple

For Research Use Only

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