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Invitrogen™ MKL1 Polyclonal Antibody
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Catalog No. PIPA5109961 Shop All Thermo Scientific Products
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PIPA5109961 100 μL
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Catalog No. PIPA5109961 Supplier Invitrogen™ Supplier No. PA5109961
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MPPLKSPAAF HEQRRSLERA RTEDYLKRKI RSRPERSELV RMHILEETSA EPSLQAKQLK LKRARLADDL NEKIAQRPGP MELVEKNILP VESSLKEAII VGQVNYPKVA DSSSFDEDSS DALSPEQPAS HESQGSVPSP LEARVSEPLL SATSASPTQV VSQLPMGRDS REMLFLAEQP PLPPPPLLPP SLTNGTTIPT AKSTPTLIKQ SQPKSASEKS QRSKKAKELK PKVKKLKYHQ YIPPDQKQDR GAPPMDSSYA KILQQQQLFL QLQILNQQQQ.

The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MKL1
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.85 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Mrtfa
Gene Accession No. Q8K4J6, Q969V6
Gene Alias AMKL; basic SAP and coiled-coil domains; basic SAP coiled-coil transcription activator; basic, SAP and coiled-coil domain; basic, SAP, and coiled-coil domain containing protein; Bsac; FLMKL1; KIAA1438; Mal; megakaryoblastic leukemia (translocation) 1; megakaryoblastic leukemia (translocation) 1 homolog; megakaryoblastic leukemia 1 met; megakaryoblastic leukemia 1 protein; Megakaryoblastic leukemia 1 protein homolog; Megakaryocytic acute leukemia protein; Megakaryocytic acute leukemia protein homolog; MELODY; mixed lineage leukemia; MKL (megakaryoblastic leukemia)/myocardin-like 1; MKL/myocardin-like protein 1; MKL1; MKL1-elongated derivative of yield protein; MKL1met; MRTFA; MRTF-A; myocardin related transcription factor A; myocardin-related transcription factor A
Gene Symbols Mrtfa
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human MKL1 (NP_065882.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 223701, 315151, 57591
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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