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  5. Tocris Bioscience™ ML 154

Tocris Bioscience™ ML 154

Catalog No. 516150
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Catalog No. Quantity
51-615-0 50 mg
51-611-0 10 mg
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Catalog No. 51-615-0 Supplier Tocris Bioscience™ Supplier No. 5161/50
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Description

Potent neuropeptide S receptor (NPSR) antagonist

ML 154 is a potent neuropeptide S receptor (NPSR) antagonist (pA2 = 9.98). Inhibits neuropeptide S-induced ERK phosphorylation over cAMP responses and calcium responses (IC50 values are 9.3, 22.1 and 36.5 nM, respectively). Appears to modulate addictive behavior in vivo. Displays no activity against vasopressin V1B receptors. Brain penetrant.

Specifications

Purity >99%
Quantity 50 mg
Product Type ML 154
Molecular Weight (g/mol) 545.47
Inhibitors ML 154

For Research Use Only

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