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  5. Tocris Bioscience™ (±)-ML 209

Tocris Bioscience™ (±)-ML 209
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Catalog No. 598750
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Catalog No. Quantity
59-875-0 50 mg
59-871-0 10 mg
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Catalog No. 59-875-0 Supplier Tocris Bioscience™ Supplier No. 5987/50
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Description

RORγt inverse agonist; suppresses Th17 cell differentiation

(±)-ML 209 is a RORγt inverse agonist (IC50 = 460 nM). Suppresses Th17 cell differentiation and IL17A expression in vitro. Does not suppress transcription of RORα. Minimal activity displayed on ERα, LXRα and thyroid hormone receptors (IC50 values >4.4 μM).

Specifications

CAS 1334526-14-5
Quantity 50 mg
Solubility Soluble to 100mM in DMSO
Molecular Formula C25H31NO6
Formula Weight 441.52g/mol
Color White
Product Type Inhibitor

For Laboratory Research Use Only

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