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Apexbio Technology LLC ML133 HCl 1222781-70-5 50mg
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Supplier:  Apexbio Technology LLC B219950

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ML133 HCl (CAS 1222781-70-5) is a small-molecule inhibitor that selectively targets the inward rectifier potassium channel K sub ir /sub 2 1 It exhibits concentration-dependent inhibition with an IC sub 50 /sub of 1 8 M at pH 7 4 and 290 nM at pH 8 5 The compound demonstrates minimal activity against K sub ir /sub 4 1 and K sub ir /sub 7 1 and does not affect K sub ir /sub 1 1 channels ML133 HCl is utilized in biomedical research to investigate the physiological and pathological roles of K sub ir /sub 2 1 supporting studies on potassium channel function cardiac electrophysiology and related ion channel disorders

Catalog No. 50-000-89691


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