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MLF1 Mouse anti-Human, Clone: OTI1B9, lyophilized, TrueMAB™
SDP

Catalog No. 501663115
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100 μg
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Catalog No. Quantity
50-166-3115 100 μg
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Catalog No. 50-166-3115 Supplier OriGene Supplier No. CF504746
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Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Specifications

Antigen MLF1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI1B9
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene MLF1
Gene Accession No. P58340
Gene Alias myeloid leukemia factor 1
Gene Symbols MLF1
Host Species Mouse
Immunogen Full length human recombit protein of human MLF1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4291
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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