Invitrogen™ MLK2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100616

Catalog No. PIPA5100616

Description

Antibody detects endogenous levels of total MLK2.

MAP3K10 (MLK2) is a serine/threonine kinase which has been shown to activate MAPK8/JNK and MKK4/SEK1. This kinase itself can be phoshorylated, and is thus activated by JNK kinases. MAP3K10 functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.

Specifications

• Antigen: MLK2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAP3K10
• Gene Alias: BC028668; BC046514; Map3k10; MAP3K9; MEKK10; MEKK9; mitogen activated protein kinase kinase kinase 10; mitogen-activated protein kinase kinase kinase 10; Mixed lineage kinase 2; mixed-lineage kinase 2; MKN28 derived nonreceptor_type; MKN28 derived nonreceptor_type serine/threonine kinase; MKN28 kinase; MLK1; MLK2; MST; PRKE1; protein kinase MST; serine/threonine kinase
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 269881, 4294
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q02779, Q66L42
• Gene Symbols: MAP3K10
• Immunogen: A synthesized peptide derived from human MAP3K10(Accession Q02779), corresponding to amino acid residues L320-L370.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov