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Invitrogen™ MMP10 Recombinant Rabbit Monoclonal Antibody (24 H24L21)

Catalog No. PI701288
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100 μg
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Catalog No. Quantity
PI701288 100 μg
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Catalog No. PI701288 Supplier Invitrogen™ Supplier No. 701288
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with mouse, rat, non-human primate and rabbit based on sequence homology. Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

MMP10 belongs to the matrix metalloproteinase family, and is generally secreted in its pro form, which is further modified by extracellular proteinases. As a metalloproteinase, MMP10 requires zinc and calcium as cofactors for activity. It is involved in the activation of pro-collagenase, catabolism of collagen, degradation of fibronectin, and tissue remodeling. In humans, the gene MMP10 located on chromosome 11.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MMP10
Applications Western Blot
Classification Recombinant Monoclonal
Clone 24 H24L21
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Gene MMP10
Gene Accession No. P07152, P09238
Gene Alias AV377895; matrix metallo protease; matrix metallopeptidase 10; matrix metallopeptidase 10 (stromelysin 2); matrix metalloprotease 10; matrix metalloproteinase 10; matrix metalloproteinase 10 (stromelysin 2); matrix metalloproteinase-10; MMP; Mmp10; MMP-10; MMPs; SL-2; STMY2; stromelysin 2; stromelysin-2; Transformation-associated protein 34A; transin 2; transin-2
Gene Symbols MMP10
Host Species Rabbit
Immunogen Recombinant protein corresponding to amino acids 282-476 of human MMP10.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117061, 4319
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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