Invitrogen™ MMP10 Recombinant Rabbit Monoclonal Antibody (24 H24L21)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ 701288

Catalog No. PI701288

Description

This antibody is predicted to react with mouse, rat, non-human primate and rabbit based on sequence homology. Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

MMP10 belongs to the matrix metalloproteinase family, and is generally secreted in its pro form, which is further modified by extracellular proteinases. As a metalloproteinase, MMP10 requires zinc and calcium as cofactors for activity. It is involved in the activation of pro-collagenase, catabolism of collagen, degradation of fibronectin, and tissue remodeling. In humans, the gene MMP10 located on chromosome 11.

Specifications

• Antigen: MMP10
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: P07152, P09238
• Gene Symbols: MMP10
• Immunogen: Recombinant protein corresponding to amino acids 282-476 of human MMP10.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Clone: 24 H24L21
• Conjugate: Unconjugated
• Gene: MMP10
• Gene Alias: AV377895; matrix metallo protease; matrix metallopeptidase 10; matrix metallopeptidase 10 (stromelysin 2); matrix metalloprotease 10; matrix metalloproteinase 10; matrix metalloproteinase 10 (stromelysin 2); matrix metalloproteinase-10; MMP; Mmp10; MMP-10; MMPs; SL-2; STMY2; stromelysin 2; stromelysin-2; Transformation-associated protein 34A; transin 2; transin-2
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 117061, 4319
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid