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Invitrogen™ MMP11 Polyclonal Antibody
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Catalog No. PIPA5120848
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PIPA5120848 100 μL
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Catalog No. PIPA5120848 Supplier Invitrogen™ Supplier No. PA5120848
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Description

Rabbit Polyclonal Antibody

Positive test controls include: Raji, 293T, Mouse lung, Mouse kidney, Mouse skeletal muscle, Mouse ovary, Mouse heart. The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space. Immunogen sequence: FRYPLSLSPD DCRGVQHLYG QPWPTVTSRT PALGPQAGID TNEIAPLEPD APPDACEASF DAVSTIRGEL FFFKAGFVWR LRGGQLQPGY PALASRHWQG LPSPVDAAFE DAQGHIWFFQ GAQYWVYDGE KPVLGPAPLT ELGLVRFPVH AALVWGPEKN KIYFFRGRDY WRFHPSTRRV DSPVPRRATD WRGVPSEIDA AFQDADGYAY FLRGRLYWKF DPVKVKALEG FPRLVGPDFF GCAEPANTFL.

Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen. The stromelysin-3 (MMP-11) gene was originally identified on the basis that it is expressed specifically in stromal cells surrounding invasive breast carcinomas. MMP-11 is localized by in situ hybridization to the long arm of chromosome 22. The MMP-11 expression is found more specifically in malignant tumors than in benign ones.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MMP11
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.59 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Mmp11
Gene Accession No. P24347, Q02853, Q499S5
Gene Alias matrix metallo protease; matrix metallopeptidase 11; matrix metallopeptidase 11 (stromelysin 3); Matrix metalloproteinase 11 (stromelysin 3); matrix metalloproteinase-11; MMP; MMP11; MMP-11; MMPs; SL-3; ST3; Stmy3; stromelysin III; stromelysin-3
Gene Symbols Mmp11
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 239-488 of human MMP11 (NP_005931.2).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17385, 25481, 4320
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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