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MMP13 Mouse anti-Human, Clone: OTI1G5, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF506689

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
MMP13 (collagense 3) plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC, and ACAN. MMP13 cleaves tripal helical collagens, including type I, II, and III collagen - but has the highest activity with soluble type II collagen. It can degrade collagen type IV, XIV, and X. MMP13 plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization, and ossification. It is required for normal embryonic bone development and ossificaiton. Mutations affecting the gene can lead to spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.Specifications
MMP13 | |
Monoclonal | |
Unconjugated | |
MMP13 | |
CLG3, MANDP1, MDST, MMP-13 | |
Mouse | |
Affinity Chromatography | |
RUO | |
4322 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
OTI1G5 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
P45452 | |
MMP13 | |
Human recombit protein fragment corresponding to amino acids 104-471 of human MMP13 produced in HEK293T cell. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG2a |
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