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Invitrogen™ MMP24 Polyclonal Antibody
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Catalog No. PIPA579682
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100 μg
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PIPA579682 100 μg
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Catalog No. PIPA579682 Supplier Invitrogen™ Supplier No. PA579682
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: PANC Cell, HELA Cell, SMMC Cell, A549 Cell.

All cells within tissues are surrounded by an extracellular matrix (ECM) giving the tissues shape and structure. The ECM is constantly being remodeled and constant communication is maintained between cells through this matrix. Secreted proteins, termed matrix metalloproteinases (MMPs), are involved in the modulation of cell-matrix interactions. MMPs are Zn (2+)-binding endopeptidases that degrade various components of the ECM. MMPs are enzymes implicated in normal and pathologic tissue remodeling processes, wound healing, angiogenesis, and tumor invasion. These enzymes are very potent when active, and are associated with extracellular space inhibitors called TIMPs (tissue inhibitors of matrix metalloproteinases). TIMPs have been shown to block tumor cell invasion suggesting that they act as metastasis suppressor genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MMP24
Applications Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
Gene MMP24
Gene Accession No. Q99PW6, Q9R0S2, Q9Y5R2
Gene Alias AU040325; matrix metallo protease; matrix metallopeptidase 24; matrix metallopeptidase 24 (membrane-inserted); matrix metalloproteinase 24; matrix metalloproteinase 24 (membrane-inserted); matrix metalloproteinase-21; Matrix metalloproteinase-24; membrane type 5-MMP; membrane-type 5 matrix metalloproteinase; membrane-type matrix metalloproteinase 5; Membrane-type-5 matrix metalloproteinase; MMP; Mmp21; MMP-21; Mmp24; MMP-24; MMP25; MMPs; MT5MMP; Mt5-mmp; MT-MMP 5; MTMMP5; MT-MMP5; Processed matrix metalloproteinase-24; RP4-614O4.10
Gene Symbols MMP24
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human MMP24 (208-225aa YHEIKSDRKEADIMIFFA).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10893, 17391, 83513
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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