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Invitrogen™ MMP27 Polyclonal Antibody
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Catalog No. PA549724
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100 μL
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PA549724 100 μL
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Catalog No. PA549724 Supplier Invitrogen™ Supplier No. PA549724
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous level of total MMP27 protein.

Metalloproteinases (MMPs) are a family of proteins that are involved in the breakdown of the extracellular matrix during normal cellular events, including reproduction, tissue remodeling and embryonic development. MMPs are crucial in tumor invasion and building of metastatic formations because of their ability to degrade extracellular matrix proteins such as fibronectin, laminin, gelatins and/or collagen. MMP-27 (matrix metallopeptidase 27) is a 513 amino acid secreted protein that is expressed in B-cells. Belonging to the peptidase M10A family, MMP-27 contains four hemopexin-like domains, which is suggested to be involved in substrate recognition. MMP-27, along with other MMP family members, is associated with breast cancer development and tumor progression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MMP27
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene MMP27
Gene Accession No. Q9H306
Gene Alias Gm180; matrix metallo protease; matrix metallopeptidase 27; matrix metalloprotease 27; matrix metalloproteinase 27; matrix metalloproteinase-27; MMP; MMP27; MMP-27; MMPs; UNQ2503/PRO5992
Gene Symbols MMP27
Host Species Rabbit
Immunogen Synthetic peptide corresponding to a region derived from 440-452 amino acids of Human matrix metallopeptidase 27.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 234911, 64066
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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