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Invitrogen™ MMP3 Recombinant Rabbit Monoclonal Antibody (JM46-22)
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Catalog No. PIMA542477
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100 μL
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PIMA542477 100 μL
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Catalog No. PIMA542477 Supplier Invitrogen™ Supplier No. MA542477
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: Human liver tissue lysate, rat liver tissue lysate, rat kidney tissue, human liver tissue, human placenta tissue, mouse liver tissue. Subcellular Location: extracellular matrix.

MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted in its pro-protein form, and is activated by extracellular proteinase cleavage. MMP3 is capable of binding to zinc and calcium ions, and has metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin. It is involved in normal cellular processes such as wound repair and tissue remodeling. Mutations in the gene can result in coronary heart disease 6.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MMP3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone JM46-22
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene MMP3
Gene Accession No. P03957, P08254, P28862
Gene Alias CHDS6; EC 3.4.24.17; EMS-2; matrix metallo protease; matrix metallopeptidase 3; matrix metallopeptidase 3 (stromelysin 1, progelatinase); matrix metalloproteinase 3; matrix metalloproteinase 3 (stromelysin 1, progelatinase); matrix metalloproteinase 3 precursor; matrix metalloproteinase-3; metalloproteinase 3 receptor; MMP; MMP10; MMP3; MMP-3; MMP-3 protein; MMPs; progelatinase; proteoglycanase; SL-1; SLN1; SLN-1; STMY; STMY1; Str1; STR-1; stromelysin; stromelysin 1; Stromelysin1; stromelysin-1; Transin1; Transin-1
Gene Symbols MMP3
Host Species Rabbit
Immunogen Synthetic peptide within C-terminal human MMP3.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171045, 17392, 4314
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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