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MMSET / WHSC1 Monoclonal Antibody (29D1), Active Motif™
SDP

Catalog No. 501992925
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50-199-2925 10 μg
50-199-2924 100 μg
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Catalog No. 50-199-2925 Supplier Active Motif Supplier No. 39880
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Mouse Monoclonal Antibody

This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.

Specifications

Antigen MMSET / WHSC1
Applications ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone 29D1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene NSD2
Gene Accession No. O96028
Gene Alias 5830445G22Rik; 9430010A17Rik; AW555663; C130020C13Rik; D030027O06Rik; D930023B08Rik; Histone-lysine N-methyltransferase NSD2; IL5 promoter REII region-binding protein; KIAA1090; mKIAA1090; MMSET; multiple myeloma SET domain containing protein type III; Multiple myeloma SET domain-containing protein; NSD2; nuclear receptor binding SET domain protein 2; Nuclear SET domain-containing protein 2; probable histone-lysine N-methyltransferase NSD2; Protein trithorax-5; REIIBP; RGD1565590; trithorax/ash1-related protein 5; TRX5; WHS; WHSC1; Whsc1l; Wolf-Hirschhorn syndrome candidate 1; Wolf-Hirschhorn syndrome candidate 1 (human); Wolf-Hirschhorn syndrome candidate 1 protein; Wolf-Hirschhorn syndrome candidate 1 protein homolog
Gene Symbols NSD2
Host Species Mouse
Immunogen This MMSET / WHSC1 antibody was raised against a recombinant protein corresponding to amino acids 1-647 of human MMSET-I.
Purification Method Protein G
Quantity 10 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7468
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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