Invitrogen™ MNT Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5143899

Catalog No. PIPA5143899

Description

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human Raji whole cell, human A549 whole cell, human HEK293 whole cell, human K562 whole cell, human PC-3 whole cell, human Caco-2 whole cell. IHC: human liver cancer tissue, human liver cancer tissue. ICC/IF: A549 cell. Flow: A431 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.

Specifications

• Antigen: MNT
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MNT
• Gene Alias: BHLHD3; Class D basic helix-loop-helix protein 3; MAD6; max binding protein; MAX network transcriptional repressor; max-binding protein MNT; Max-interacting protein; MNT; MNT, MAX dimerization protein; MXD6; Myc antagonist MNT; Protein ROX; Rox
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4335
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: Q99583
• Gene Symbols: MNT
• Immunogen: E.coli-derived human MNT recombinant protein (Position: H381-N564).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG