BRAF, Mouse, Clone: 1H12F1, 1H12G10, 1F12F11C9, Abnova™

Mouse monoclonal antibody raised against recombinant BRAF.

Manufacturer:  Abnova Corporation MAB10455

Catalog No. 89-108-641

Description

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, nonsmall cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq

Specifications

• Antigen: BRAF
• Clone: 1F12F11C9, 1H12F1, 1H12G10
• Description: Mouse monoclonal antibody raised against recombinant BRAF.
• Formulation: In ascitic (0.03% sodium azide)
• Format: Liquid
• Gene Symbols: BRAF
• Immunogen: Recombinant protein corresponding to human BRAF.
• Quantity: 100 uL
• Storage Requirements: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Human

• Applications: ELISA, Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) ELISA (1:10000) The optimal working dilution should be determined by the end user.
• Gene: BRAF
• Gene Alias: B-RAF1/BRAF1/FLJ95109/MGC126806/MGC138284/RAFB1
• Host Species: Mouse
• Isotype: IgG1
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 673