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Description
The OX-35 clone has been reported to react with the CD4 antigen on most thymocytes, a subpopulation of mature T lymphocytes (i.e. MHC class II-restricted T cells, including most T helper cells), monocytes, macrophages, some dendritic cells, and microglia. CD4 is an antigen coreceptor on the T-cell surface that interacts with MHC class II molecules on antigen-presenting cells. It participates in T-cell activation through it's association with the T-cell receptor complex and protein tyrosine kinase Lck. The OX-35 clone has been reported to bind to a different epitope of CD4 than that recognized by the W3/25 and OX-38 clones.
Specifications
Specifications
| Antigen | CD4 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | OX-35 |
| Concentration | 0.2mg/mL |
| Conjugate | APC-Cyanine7 |
| Description | Cd4; CD4 antigen; p55; W3/25 antigen; T-cell surface glycoprotein CD4 |
| Formulation | Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Rat T-cell blasts |
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