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COL11A2, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89104307 Shop All Abnova Corporation Products
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Catalog No. 89-104-307 Supplier Abnova Corporation Supplier No. H00001302A01
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Mouse polyclonal antibody raised against a partial recombinant COL11A2.

This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant nonsyndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive nonsyndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6. [provided by RefSeq

Sequence: APPVDVLRALRFPSLPDGVRRAKGICPADVAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYEDQT

Specifications

Antigen COL11A2
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Mouse polyclonal antibody raised against a partial recombinant COL11A2.
Formulation 50% glycerol
Gene COL11A2
Gene Accession No. NM_080680
Gene Alias DFNA13/DFNB53/HKE5/PARP/STL3
Gene Symbols COL11A2
Host Species Mouse
Immunogen COL11A2 (NP_542411, 29 a.a. to 128 a.a) partial recombinant protein with GST tag.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1302
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Antisera
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