FCER1A, Mouse, Clone: CRA2, Abnova™

Catalog No.	Quantity
89-113-245	100 μg

Catalog No. 89-113-245 Supplier Abnova Corporation Supplier No. MAB7946

Description

Mouse monoclonal antibody raised against recombinant FCER1A.

The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response. The IgE receptor consists of 3 subunits: alpha, beta (MIM 147138), and gamma (MIM 147139); only the alpha subunit is glycosylated.[supplied by OMIM

Specifications

• Antigen: FCER1A
• Applications: Flow Cytometry, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: CRA2
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against recombinant FCER1A.
• Dilution: Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (50% glycerol)
• Gene: FCER1A
• Gene Alias: FCE1A/FcERI
• Gene Symbols: FCER1A
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human FCER1A.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2205
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1 κ