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HLA-DQA1, Mouse, Clone: TAL 4.1, Abnova™

Catalog No. 89113113 Shop All Abnova Corporation Products
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89-113-113 100 μg
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Catalog No. 89-113-113 Supplier Abnova Corporation Supplier No. MAB7017
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Description

Mouse monoclonal antibody raised against native HLA-DQA1.

HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq

Specifications

Antigen HLA-DQA1
Applications ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
Classification Monoclonal
Clone TAL 4.1
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against native HLA-DQA1.
Dilution The optimal working dilution should be determined by the end user.
Formulation In PBS
Gene HLA-DQA1
Gene Alias CD/CELIAC1/DQ-A1/FLJ27088/FLJ27328/GSE/HLA-DQA/MGC149527
Gene Symbols HLA-DQA1
Host Species Mouse
Immunogen Native purified HLA-DQA1 from whole cells from the B line WT46.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3117
Test Specificity HLA DQ (TAL 4.1). Predicted molecular weight 28 KDa.
Target Species Human
Content And Storage Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG2b
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