HLA-DRA, Mouse, Clone: TAL 1B5, Abnova™

Catalog No.	Quantity
89-113-114	100 μg

Catalog No. 89-113-114 Supplier Abnova Corporation Supplier No. MAB7019

Description

Mouse monoclonal antibody raised against HLA-DRA.

HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq

Specifications

• Antigen: HLA-DRA
• Applications: ELISA, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: TAL 1B5
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against HLA-DRA.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS
• Gene: HLA-DRA
• Gene Alias: HLA-DRA1
• Gene Symbols: HLA-DRA
• Host Species: Mouse
• Immunogen: Human bristol 8 separated alpha chain preparation
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3122
• Test Specificity: HLA DR (TAL 1B5). Western blots to dimer and DR alpha chain. MW 33KDa.
• Target Species: Human
• Content And Storage: Store at 4°C for short term. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1