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Mouse anti-Human CD59/MACIF/MIRL/Protectin Monoclonal Antibody, Clone: BRA-10G, Epredia™ LabVision

Catalog No. MS507P1ABX Shop All Epredia Products
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200 μL
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200μg/mL
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Catalog No. Quantity Concentration
MS507P1ABX 100 μL 1mg/mL
MS507P0 100 μL 200μg/mL
MS507PABX 200 μL 1mg/mL
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Mouse Monoclonal Antibody

CD59 (also known as membrane attack complex inhibition factor (MACIF), membrane inhibitor of reactive lysis (MIRL), homologous restriction factor (HRF20), and Protectin) is a glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein. CD59 is widely distributed on cells in all tissues. It inhibits formation of MAC, thus protecting cells from complement mediated lysis. The expression of CD59 on erythrocytes is important for their survival. Genetic defects in GPI-anchor attachment that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal hemoglobulinuria (PNH).

Host Species: Mouse
Clone: BRA-10G
Isotype: IgG1/κ
Cross Reactivity: Human, Others not-known
Epitope: Not determined
Immunogen: Human K562 tumor cells
Molecular Weight: 20kDa
Positive Control: Daudi, CEM, K562, Jurkat, Raji, and human lymphocytes. Lymph node or tonsil.
Cellular Localization: Cell membrane

Flow Cytometry, Immunohistochemistry, Immunoprecipitation

Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly

Specifications

Antigen CD59/MACIF/MIRL/Protectin Ab-2
Classification Monoclonal
Concentration 1mg/mL
Host Species Mouse
Immunogen Human K562 tumor cells
Quantity 100 μL
Primary or Secondary Primary
Target Species Human
Form Purified
Isotype IgG1 κ
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