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Ly-108 Mouse anti-Mouse, Brilliant Violet 421, Clone: 13G3, BD Optibuild™
Shop All BD Biosciences ProductsDescription
The 13G3 monoclonal antibody specifically binds to Lymphocyte antigen 108, Ly-108. Ly-108 is a member of the signaling lymphocytic activation molecule (SLAM) family of immune receptors. Ly-108 is a type 1 transmembrane glycoprotein adhesion receptor that is expressed by T cells, NKT cells, B cells, NK cells, macrophages, dendritic cells and neutrophils. Ly-108 plays multiple roles in innate and adaptive immunity including costimulation of NK cell cytotoxicity and T cell cytokine responses. Moreover, Ly-108 has been implicated in autoimmunity.
The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.
Specifications
Specifications
| Antigen | Ly-108 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 13G3 |
| Concentration | 0.2mg/mL |
| Conjugate | Brilliant Violet 421 |
| Description | Slamf6; SLAM family member 6; KAL1; NTB-A; SF2000 |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | WT thymocytes |
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For Research Use Only
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