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S100A9 Mouse anti-Human, PE, Clone: 1H9, BD

Catalog No. BDB565793 Shop All BD Biosciences Products
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BDB565793 50 Tests
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Catalog No. BDB565793 Supplier BD Biosciences Supplier No. 565793

Description

Mouse Monoclonal Antibody

The 1H9 monoclonal antibody specifically binds to S100 calcium binding protein A9 (S100A9), which is also known as Migration inhibitory factor-related protein 14 (MRP-14), Calgranulin-B (CAGB), Calprotectin L1H subunit, or Leukocyte L1 complex heavy chain. S100A9 is an ∽14 kDa member of the S100 family of EF-hand calcium-binding proteins. S100A9 is expressed in granulocytes, monocytes, and some secretory epithelial cells. A soluble form of S100A9 can also be found in the serum. S100A9 functions as a chemoattractant for neutrophils and monocytes. S100A9 can associate with another S100 family member, S100A8 (also known as, MRP-8) to form a MRP-8/14 heterodimer called Calprotectin or Cystic fibrosis antigen (CFAG). The heterodimer has a wide range of functions, such as playing roles in arachidonic acid metabolism and stimulation of the innate immune system through its interaction with CD284 (Toll-like receptor 4/TLR4).

TRUSTED_SUSTAINABILITY

Specifications

Antigen S100A9
Applications Flow Cytometry, Immunocytochemistry
Classification Monoclonal
Clone 1H9
Conjugate PE
Description MRP14; CAGB; CFAG; CGLB; L1AG; LIAG; MAC387; MIF; NIF; P14; 60B8AG
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human MRP-14 Recombinant Protein
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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