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S100A9 Mouse anti-Human, PE, Clone: 1H9, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 565793

Catalog No. BDB565793

Item Discontinued This item has been discontinued by the Fisher Scientific channel. Please to view product availability in your area.


Description

Description

The 1H9 monoclonal antibody specifically binds to S100 calcium binding protein A9 (S100A9), which is also known as Migration inhibitory factor-related protein 14 (MRP-14), Calgranulin-B (CAGB), Calprotectin L1H subunit, or Leukocyte L1 complex heavy chain. S100A9 is an ∽14 kDa member of the S100 family of EF-hand calcium-binding proteins. S100A9 is expressed in granulocytes, monocytes, and some secretory epithelial cells. A soluble form of S100A9 can also be found in the serum. S100A9 functions as a chemoattractant for neutrophils and monocytes. S100A9 can associate with another S100 family member, S100A8 (also known as, MRP-8) to form a MRP-8/14 heterodimer called Calprotectin or Cystic fibrosis antigen (CFAG). The heterodimer has a wide range of functions, such as playing roles in arachidonic acid metabolism and stimulation of the innate immune system through its interaction with CD284 (Toll-like receptor 4/TLR4).

TRUSTED_SUSTAINABILITY
Specifications

Specifications

S100A9
Monoclonal
PE
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Human MRP-14 Recombinant Protein
50 Tests
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry, Immunocytochemistry
1H9
MRP14; CAGB; CFAG; CGLB; L1AG; LIAG; MAC387; MIF; NIF; P14; 60B8AG
Mouse
Affinity Purified
RUO
Human
IgG1 κ
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