Terminal Transferase (TdT) Mouse anti-Human, Alexa Fluor 647, Clone: E17-1519, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 565231
The E17-1519 monoclonal antibody specifically recognizes Terminal deoxynucleotidyl transferase (TdT), which is also known as Terminal transferase, or DNA nucleotidylexotransferase (DNTT). TdT is a 60 kDa nuclear polymerase that catalyzes the template-independent addition of deoxynucleotides to the 3'-hydroxyl termini of single-stranded oligonucleotide primer segments. TdT can contribute to antigen receptor diversity by N region diversification of rearranging immunoglobulin heavy chain and T cell receptor gene segments during pre-B and pre-T cell development. It is also expressed by certain lymphomas and leukemias.
|Terminal Transferase (TdT)|
|TdT; DNTT; Terminal transferase; Terminal addition enzyme|
|Purified Human TdT|
|Flow Cytometry, Immunocytochemistry|
|Alexa Fluor 647|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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