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Terminal Transferase (TdT) Mouse anti-Human, Alexa Fluor 647, Clone: E17-1519, BD
Shop All BD Biosciences ProductsDescription
The E17-1519 monoclonal antibody specifically recognizes Terminal deoxynucleotidyl transferase (TdT), which is also known as Terminal transferase, or DNA nucleotidylexotransferase (DNTT). TdT is a 60 kDa nuclear polymerase that catalyzes the template-independent addition of deoxynucleotides to the 3'-hydroxyl termini of single-stranded oligonucleotide primer segments. TdT can contribute to antigen receptor diversity by N region diversification of rearranging immunoglobulin heavy chain and T cell receptor gene segments during pre-B and pre-T cell development. It is also expressed by certain lymphomas and leukemias.
Specifications
Specifications
| Antigen | Terminal Transferase (TdT) |
| Applications | Flow Cytometry, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | E17-1519 |
| Conjugate | Alexa Fluor 647 |
| Description | TdT; DNTT; Terminal transferase; Terminal addition enzyme |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Purified Human TdT |
| Purification Method | Affinity Purified |
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