TLR2, Mouse, Monoclonal Antibody, Abnova™

Catalog No.	Quantity
89-113-538	100 μg

Catalog No. 89-113-538 Supplier Abnova Corporation Supplier No. MAB8719

Description

Mouse monoclonal antibody raised against synthetic peptide of TLR2.

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq

Specifications

• Antigen: TLR2
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic peptide of TLR2.
• Dilution: Western Blot (1:100-1:2000) ELISA (1:5000-1:20000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (0.02% sodium azide, 1% BSA, 50% glycerol)
• Gene: TLR2
• Gene Accession No.: NM_003264.3
• Gene Alias: CD282/TIL4
• Gene Symbols: TLR2
• Host Species: Mouse
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to C-terminus residues of human TLR2.
• Purification Method: Protein G purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7097
• Test Specificity: This antibody is specific to TLR2.
• Target Species: Human
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid