Gibco™ Mouse FGF-10 Recombinant Protein, PeproTech®

Description

Recombinant Protein

Recombinant Murine FGF-10 is a 17.0 kDa protein consisting of 148 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.

Specifications

• Accession Number: O35565
• For Use With (Application): Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 14165
• Molecular Weight (g/mol): 17 kDa
• Name: Mouse FGF-10
• Quantity: 25 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: AEY17; BB213776; FGF; Fgf10; FGF-10; Fibroblast growth factor; Fibroblast growth factor 10; Gsfaey17; Keratinocyte growth factor 2; produced by fibroblasts of urinary bladder lamina propria
• Common Name: FGF10
• Gene Symbol: FGF10
• Biological Activity: Determined by dose-dependent ability to reduce tetrazolium salt, WST-8, by dehydrogenase activities of BaF3 cells expressing FGF receptors using Cell Counting Kit-8 (CCK-8).
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: SSAGRHVRSY NHLQGDVRWR RLFSFTKYFL TIEKNGKVSG TKNEDCPYSV LEITSVEIGV VAVKAINSNY YLAMNKKGKL YGSKEFNNDC KLKERIEENG YNTYASFNWQ HNGRQMYVAL NGKGAPRRGQ KTRRKNTSAH FLPMTIQT
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 95% by SDS-PAGE gel and HPLC analyses.