Invitrogen™ Mouse Flt-3 Ligand (FLT3L) Recombinant Protein

Catalog No.	Quantity
PIRP8665	10 μg

Catalog No. PIRP8665 Supplier Invitrogen™ Supplier No. RP8665

Description

Recombinant Protein

Reconstitute in sterile water to 0.1 mg/mL. Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

FLT3LG (Fms Related Tyrosine Kinase 3 Ligand) is a Protein Coding gene. Diseases associated with FLT3LG include Aplastic Anemia and Brain Cancer. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Ras signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and cytokine activity. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts.

Specifications

• Accession Number: P49772
• Concentration: 0.1 mg/mL
• For Use With (Application): Control, Bioactivity
• Formulation: 10mM sodium phosphate with no preservative; pH 7.5
• Gene ID (Entrez): 14256
• Molecular Weight (g/mol): 18.6 kDa
• Name: Mouse Flt-3 Ligand (FLT3L)
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 10 μg
• Source: E. coli
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Endotoxin Concentration: ≤0.1 EU/μg
• Gene Alias: FL; Flt 3 ligand; Flt3; Flt3 L; Flt3 ligand; Flt3l; Flt3lg; fms related receptor tyrosine kinase 3 ligand; fms related tyrosine kinase 3 ligand; FMS-like tyrosine kinase 3 ligand; fms-related tyrosine kinase 3; fms-related tyrosine kinase 3 ligand; H-FLT-3-L; Ly72L; M-FLT-3-L; NEWGENE_2322792; SL cytokine
• Common Name: FLT3LG
• Gene Symbol: Flt3l
• Biological Activity: ED50 = 10 ng/mL; determined by the dose-dependent proliferation of OCI-AML5 cells.
• Product Type: Protein
• Conjugate: Unconjugated
• Species: E. coli
• Recombinant: Recombinant
• Sequence: MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Activity: ED50 ≤ 10 ng/mL; determined by the dose-dependent proliferation of OCI-AML5 cells.
• Expression System: E. coli
• Form: Lyophilized
• Protein Subtype: Recombinant
• Purity or Quality Grade: ≥95%

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov