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Gibco™ Mouse GDNF Recombinant Protein, PeproTech®
SDP

E. coli Recombinant Protein

Supplier:  Gibco™ 45044250UG

Encompass

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Catalog No. 45044250UG


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Description

Description

GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

P48540
protein with no preservative
30.2
250 μg
-20°C
<1 EU/μg
GDNF
Unconjugated
MSPDKQAAAL PRRERNRQAA AASPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCESAETMY DKILKNLSRS RRLTSDKVGQ ACCRPVAFDD DLSFLDDNLV YHILRKHSAK RCGCI
≥ 98% by SDS-PAGE gel and HPLC analyses.
Functional Assay
14573
Mouse GDNF
E. coli
RUO
AI385739; Astrocyte-derived trophic factor; ATF; ATF1; ATF2; Gdnf; glial cell derived neurotrophic factor; glial cell line derived neurotrophic factor; Glial cell line derived neutrophic factor; glial cell line-derived neurotrophic factor; gndf; HFB1-GDNF; hGDNF; H-GDNF; HSCR3; mGDNF; neurotrophic factor
Mouse
Recombinant
Lyophilized
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