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  5. Invitrogen™ Mouse HGFR/MET ELISA Kit 

Invitrogen™ Mouse HGFR/MET ELISA Kit

Catalog No. EM37RBX5
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Description

ELISA

Mouse HGFR/MET quantitates mouse HGFR/MET in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse HGFR/MET.

MET (cMET) is a receptor-like tyrosine kinase whose dysregulation has been linked to many types of human malignancies. After activation of the ligand, MET interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3. There interactions lead to the activation of signaling cascades including RAS-ERK, PI3, kinase-AKT, and PLCgamma-PKC. MET plays a role in embryonic development including gastrulation, development of muscles and neurons, angiogenesis, and kidney formation. It also plays a role in adults including wound healing, organ regeneration, and tissue remodeling. MET has been linked to cancers including gastric, renal, and breast; therefore, making it a target for cancer therapeutics and diagnostic testing.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number AI838057; AUTS9; bHLHe59; CG1705; CG1705 gene product from transcript CG1705-RB; CG1705-PA; CG1705-PB; cMet; c-met; DFNB97; Dmel\CG1705; Dmel
Assay Range 0.082 to 20 ng/mL
Assay Sensitivity 0.08 ng/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 17295
Gene Symbol MET
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 5 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target c-Met
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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