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Invitrogen™ Mouse IgG1 Isotype Control (CT6)

Catalog No. 01671020
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Catalog No. Quantity
01-671-020 1 mL
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Catalog No. 01-671-020 Supplier Invitrogen™ Supplier No. SA135641
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Description

Mouse Monoclonal Isotype Control

The antibody reacts with a Guinea pig lymphocyte subset probably analog to human CD8 (cytotoxic/suppressor) subset. CD8 comprises 2 subunits, alpha and beta and exists as either an alpha/alpha homodimer or an alpha/beta heterodimer. Sequence suggests that guinea pig CD8 is more closely related to human than rat or mouse CD8. Although this monoclonal originally was developed for the detection of a Guinea pig lymphocyte subset, it also can be used as a negative control for the JSB-1 monoclonal antibodies because it is of the same IgG subclass.

Mouse IgG1 is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen. It is the most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response. Mouse IgG1 is composed of two heavy chains and two light chains, and it is involved in opsonization, complement activation, and antibody-dependent cell-mediated cytotoxicity. It is also involved in the regulation of immune responses, including the activation of T cells and the inhibition of B cell activation. Mouse IgG1 is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry. It is also used in therapeutic applications, such as immunotherapy and vaccine development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Mouse IgG1
Applications Control, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone CT6
Concentration 1 mg/mL
Conjugate Unconjugated
Dilution Assay Dependent
Formulation PBS with 0.1% sodium azide
Gene Alias IgG1; Igh-4; Ighg1; Immunoglobulin G; Immunoglobulin G1; immunoglobulin heavy constant gamma 1 (G1m marker); ImmunoglobulinG; ImmunoglobulinG1; VH7183
Host Species Mouse
Immunogen Proprietary Immunogen.
Purification Method Purified
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Isotype Control (Primary)
Target Species Not Applicable
Content And Storage 4°C
Product Type Isotype Control
Form Liquid
Isotype IgG1
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