Invitrogen™ Mouse IgG2a Isotype Control (MOPC-173), DyLight™ 488

Mouse Monoclonal Isotype Control

Supplier:  Invitrogen™ MA1193D488

Catalog No. MA1193D488

Description

This antibody reacts with an unknown epitope. It does not react with a variety of resting, activated, live, and fixed mouse, rat and human tissues. MA1-193-D488 can be used as a negative control in any immunoassay where a DyLight 488-conjugated primary antibody of the mouse IgG2a isotype is used. DyLight 488 has an excitation/emission of 493/518nm.

Mouse IgG2a is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen. It is the second most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response. Mouse IgG2a is composed of two heavy chains and two light chains, and it is involved in opsonization, complement activation, and antibody-dependent cell-mediated cytotoxicity. It is also involved in the regulation of immune responses, including the activation of T cells and the inhibition of B cell activation. Mouse IgG2a is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry. It is also used in therapeutic applications, such as immunotherapy and vaccine development.

Specifications

• Antigen: Mouse IgG2a
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 0.2% BSA and 15mM sodium azide
• Host Species: Mouse
• Purification Method: Size-exclusion chromatography
• Regulatory Status: RUO
• Target Species: Not Applicable
• Product Type: Isotype Control
• Isotype: IgG2a κ

• Applications: Control, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: MOPC-173
• Conjugate: DyLight 488
• Gene Alias: IgG2; Immunoglobulin G; Immunoglobulin G2; ImmunoglobulinG; ImmunoglobulinG2
• Immunogen: The transplantable plasmacytoma MOPC-173 was induced by intraperitoneal injection of mineral oils into BALB/c mice.
• Quantity: 100 μg
• Primary or Secondary: Isotype Control (Primary)
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid