Invitrogen™ Mouse IL-2 Recombinant Protein

Catalog No.	Quantity
PIRP8605	20 μg

Catalog No. PIRP8605 Supplier Invitrogen™ Supplier No. RP8605

Description

Recombinant Protein

IL-2 (mouse) Recombinant Protein, RP-8605, from Invitrogen.

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli. Recombinant mouse IL-4 is a non-glycosylated protein, containing 121 amino acids, with a molecular weight of 13.5 kDa. Purity is typically greater than 98% and endotoxin level less than 1 EU/ug. The expected biological activity (ED50) is determined by the dose-dependent induction of HT-2 cell proliferation and is typically less than 2ng/mL. The specific activity of this protein is 5x10^5 units/mg. Reconstitute using sterile water at 0.1mg/mL and centrifuge prior to opening vial. Gently pipet solution down the sides of the vial. DO NOT VORTEX sample. Store reconstituted material at -20°C and add 0.1% BSA for additional stability. Amino acid sequence: MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S.

Specifications

• Accession Number: P04351
• Concentration: 0.1mg/mL
• For Use With (Application): Control
• Formulation: 0.01M citric acid, water with no preservative; pH 4.0
• Gene ID (Entrez): 16183
• Name: Mouse IL-2
• pH Range: 4.0
• Quantity: 20 μg
• Source: E. Coli
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: M-IL-2
• Common Name: Mouse IL-2
• Gene Symbol: Il2
• Specific Reactivity: Mouse
• Conjugate: Unconjugated
• Cross Reactivity: Ms
• Species: E. coli
• Recombinant: Recombinant
• Form: Lyophilized
• Protein Subtype: Recombinant
• Purity or Quality Grade: Size-exclusion - Dialysis