Invitrogen™ Mouse RIP3 Synthetic Peptide

Description

Synthetic Peptide

RIP3 Synthetic Peptide, PEP-0081, from Invitrogen.

RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, which contains a C-terminal domain unique from other RIP family members. RIPK3 is predominantly localized to the cytoplasm, and specifically, are colocalized in the mitochondrion which can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. RIPK3 is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor and caspase-8 prevents RIPK3-dependent necrosis without inducing apoptosis by functioning in a proteolytically active complex with CFLAR and that this complex is required for the protective function.

Specifications

• Gene ID (Entrez): 56532
• Species: Mouse
• Purification Method: purified
• Accession Number: Q9QZL0
• Common Name: Mouse RIP3
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Symbol: Ripk3
• Lyophilized: No
• Preservative: 0.02% sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO - research use only
• Storage Buffer: PBS