Gibco™ Mouse SF-20 Recombinant Protein, PeproTech®

Catalog No. 21025250UG

Supplier: Gibco™ 21025250UG

Description

Recombinant Protein

Recombinant Murine SF-20 is a 15.8 kDa protein containing 143 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

The interleukins are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. IL-25 (also called SF20/IL-25) is a secreted bone marrow stroma-derived growth factor cytokine that is derived from Th2 T-cells. IL-25 belongs to the IL-17 cytokine family and is capable of amplifying allergic type inflammatory responses by its actions on other cell types. IL-25 binds to mouse thymic shared antigen-1 and supports lymphoid cell proliferation. Infusion of mice with IL-25 induces IL-4, IL-5, and IL-13 gene expression. IL-25 induced mice also develop epithelial cell hyperplasia, increased mucus secretion, and airway hyperreactivity, suggesting that IL-25 may be an important mediator of allergic disease via production of IL-4, IL-5, IL-13 and eotaxin.

Specifications

• Accession Number: Q9CPT4
• For Use With (Application): ELISA, Functional Assay, Western Blot
• Formulation: protein with no preservative
• Gene ID (Entrez): 28106
• Molecular Weight (g/mol): 15.8 kDa
• Name: Mouse SF-20
• Quantity: 250 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: C19orf10; CS010; D17Wsu104e; EUROIMAGE1875335; IL 25; IL 27; Il25; IL27; IL27w; interleukin 25; interleukin 27 working designation; Interleukin25; interleukin-25; LOC501282; Ly6elg; Mydgf; myeloid derived growth factor; myeloid-derived growth factor; R33729 1; R33729_1; R337291; SF20; similar to lymphocyte antigen 6 complex, locus E ligand; stromal cell-derived growth factor SF20; UPF0556 protein C19orf10; UPF0556 protein C19orf10 homolog
• Common Name: C19orf10
• Gene Symbol: MYDGF
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: MVSEPTTVPF DVRPGGVVHS FSQDVGPGNK FTCTFTYASQ GGTNEQWQMS LGTSEDSQHF TCTIWRPQGK SYLYFTQFKA ELRGAEIEYA MAYSKAAFER ESDVPLKSEE FEVTKTAVSH RPGAFKAELS KLVIVAKAAR SEL
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.