MP Biomedicals™ Catalase from Bovine Liver

Description

Natural antioxidant used to study roles of reactive oxygen species in gene expression and apoptosis

A homotetrameric enzyme that is primarily located in peroxisomes. It is a tetramer consisting of 4 equal subunits with a molecular weight of 60kDa each. Each subunit contains iron bound to a protoheme IX group. The enzyme also strongly binds NADP, which is in close proximity to the heme group (13.7Å apart). Catalase can also react with alkylhydrogen peroxides such as methylperoxide and ethylperoxide and does not require any activator for exhibiting its catalytic activity. Catalase activity is constant over the pH range of 4.0 to 8.5.

 

• CAS Number: 9001-05-2
• EC Number: 232-577-1
• MDL Number: MFCD00081483
• Format: Clear, pale yellow solution
• Specific Activity: ∽30,000U/mL; ≥40,000U/mg protein
• Extinction Coefficient: 36.5 (276nm)
• Sterile Aqueous Solution, miscible in water

 

Specifications

• Concentration: ≈30,000 U/mL, ≈40,000 U/mg Protein
• Color: Pale Yellow
• pH: 4 to 8.5
• For Use With (Application): Used as an antioxidant in cell culture media, used to study the role of ROSs in gene expression and apoptosis, mainly in cancer researches and it is also used to eliminate H2O2 from enzymatic Oxidation reactions
• CAS: 9001-05-2
• Content And Storage: 4°C
• Sterility: Sterile Aqueous Solution
• Source: Bovine liver
• Quantity: 10 mL
• Product Type: Catalase
• Molecular Weight (g/mol): 250
• Form: Liquid