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Tocris Bioscience™ MPEP hydrochloride

Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors

Manufacturer:  Tocris Bioscience™ 1212/10

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Catalog No. 12-121-0


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Description

Description

MPEP hydrochloride is a potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw.
Specifications

Specifications

Observed MW: 229.71
99%
2-Methyl-6-(phenylethynyl)pyridine hydrochloride
>99%
Soluble to 100mM in DMSO
C14H11N.HCl
Group I mGluR Antagonists
219911-35-0
10 mg
Safety and Handling

Safety and Handling

Recommended Storage : Desiccate at +4°C

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