Tocris Bioscience™ MPEP hydrochloride
Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors
Manufacturer: Tocris Bioscience™ 1212/10
DescriptionMPEP hydrochloride is a potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw.
|Observed MW: 229.71|
|Soluble to 100mM in DMSO|
|Group I mGluR Antagonists|
Safety and Handling
Recommended Storage : Desiccate at +4°C
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