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Invitrogen™ MPP5 Monoclonal Antibody (OTI2D3)
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Catalog No. PIMA525916
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100 μL
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Catalog No. Quantity
PIMA525916 100 μL
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Catalog No. PIMA525916 Supplier Invitrogen™ Supplier No. MA525916
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Description

Mouse Monoclonal Antibody

MPP5 Monoclonal Antibody for Western Blot, Flow

MPP5 (Membrane Protein, Palmitoylated 5) plays a critical role in neurogenesis and hematopoiesis. This protein is crucial for establishing and maintaining cell polarity in epithelial cells and neurons. It is involved in the Par-3 complex, which contributes to maintaining tight junctions in epithelial cells. Mutations in MPP5 have been associated with severe neurologic impairments, including global developmental delay (GDD) and behavioral changes. In animal models, MPP5 is highly involved in the early differentiation of multipotent progenitors and supports long-term lineage-specific contributions, primarily in myeloid and lymphoid cells. MPP5 variants disrupt normal cellular function, leading to profound developmental and functional abnormalities.
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Specifications

Antigen MPP5
Applications Flow Cytometry, Western Blot
Classification Monoclonal
Clone OTI2D3
Concentration 0.88 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MPP5
Gene Accession No. Q8N3R9
Gene Alias 3830420B02Rik; AI255216; AI644496; FLJ12615; MAGUK p55 subfamily member 5; membrane palmitoylated protein 5; membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 5); membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); MPP5; palmitoylated 5; PALS1; protein associated with Lin Seven 1; protein associated with Lin-7 1; stardust
Gene Symbols MPP5
Host Species Mouse
Immunogen Full length human recombinant protein of MPP5 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 314259, 490740, 64398
Target Species Human, Rat, Canine
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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