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Tocris Bioscience™ Mps1-IN-1 dihydrochloride

Catalog No. 514210
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective Mps1 kinase inhibitor

Mps1-IN-1 dihydrochloride is a selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 367 nM); exhibits >1000 fold-selectivity against a panel of 352 kinases with the exceptions of ALK and Ltk. Disrupts the recruitment of Mad2 to kinetochores. Increases frequency of multipolar mitosis in U2OS cells.

Specifications

Purity >98%
CAS 1883548-93-3
Quantity 10 mg
Product Type Mps1-IN-1 dihydrochloride
Molecular Weight (g/mol) 608.58
Inhibitors Mps1-IN-1 dihydrochloride

For Research Use Only

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