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Invitrogen™ MRC2 Recombinant Rabbit Monoclonal Antibody (5I0I9)

Catalog No. MA557975
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MA557976 100 μL
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Catalog No. MA557975 Supplier Invitrogen™ Supplier No. MA557975
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: DAALPEPNVF LIFSHGLQGC LEAQGGQVRV TPACNTSLPA QRWKWVSRNR LFNLGTMQCL GTGWPGTNTT ASLGMYECDR EALNLRWHCR TLGDQLSLLL GARTSNISKP GTLERGDQTR SGQWRIYGSE EDLCALPYHE VYTIQGNSHG KPCTIPFKYD NQWFHGCTST GREDGHLWCA TTQDYGKDER WGFCPIKSND CETFWDKDQL TDSCYQFNFQ STLSWREAWA SCEQQGADLL SITEIHEQTY INGLLTGYSS TLWIGLNDLD TSGGWQWSDN SPLKYLNWES DQPDNPSEEN CGVIRTESSG GWQNRDCSIA LPYVCKKKPN ATAEPTPPDR WANVKVECEP SWQPFQGHCY RLQAEKRSWQ ESKKACLRGG GDLVSIHSMA ELEFITKQIK QEVEELWIGL NDLKLQMNFE WSDGSLVSFT HWHPFEPNNF RDSLEDCVTI WGPEGRWNDS PCNQSLPSIC KKAGQLSQG.

May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRC2
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 5I0I9
Concentration 1.08 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3
Gene MRC2
Gene Accession No. Q9UBG0
Gene Alias CD280; CLEC13E; collagen-binding factor Endo180; C-type lectin domain family 13 member E; C-type mannose receptor 2; Endo180; endocytic receptor (macrophage mannose receptor family); endocytic receptor 180; KIAA0709; Lectin lambda; macrophage mannose receptor 2; mannose receptor C type 2; mannose receptor, C type 2; mKIAA0709; Mrc2; novel lectin; UPARAP; UPAR-associated protein; urokinase-type plasminogen activator receptor-associated protein
Gene Symbols MRC2
Host Species Rabbit
Immunogen Recombinant Protein (or fragment).
Purification Method Protein A
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9902
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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