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Invitrogen™ MRGPRX2 Polyclonal Antibody
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Catalog No. PIPA5113198
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100 μg
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Catalog No. Quantity
PIPA5113198 100 μg
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Catalog No. PIPA5113198 Supplier Invitrogen™ Supplier No. PA5113198
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Description

Rabbit Polyclonal Antibody

MRGPRX2 Polyclonal Antibody for ELISA, ICC/IF, Western Blot

Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled. Has a limited expression profile, both peripheral and within the central nervous system, with highest levels in dorsal root ganglion.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRGPRX2
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene MRGPRX2
Gene Accession No. Q3UG50, Q96LB1
Gene Alias G protein-coupled receptor MRGX2; G370024M05Rik; MAS related GPR family member X2; Mas-related G protein-coupled receptor G3; MAS-related GPR, member B10; MAS-related GPR, member X2; mas-related G-protein coupled receptor member B10; Mas-related G-protein coupled receptor member X2; MGRG3; MrgB10; Mrgprb10; Mrgprx2; MRGX2
Gene Symbols MRGPRX2
Host Species Rabbit
Immunogen Recombinant Human Mas-related G-protein coupled receptor member X2 protein (286-330AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117194, 243978
Target Species Human, Mouse
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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